| Association analysis identifies 65 new breast cancer risk loci K Michailidou, S Lindström, J Dennis, J Beesley, S Hui, S Kar, A Lemaçon, ... Nature 551 (7678), 92-94, 2017 | 1310 | 2017 |
| Resistance to therapy caused by intragenic deletion in BRCA2 SL Edwards, R Brough, CJ Lord, R Natrajan, R Vatcheva, DA Levine, ... Nature 451 (7182), 1111-1115, 2008 | 1082 | 2008 |
| Beyond GWASs: illuminating the dark road from association to function SL Edwards, J Beesley, JD French, AM Dunning The American Journal of Human Genetics 93 (5), 779-797, 2013 | 897 | 2013 |
| Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer SE Bojesen, KA Pooley, SE Johnatty, J Beesley, K Michailidou, JP Tyrer, ... Nature genetics 45 (4), 371-384, 2013 | 652 | 2013 |
| Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers JD French, M Ghoussaini, SL Edwards, KB Meyer, K Michailidou, ... The American Journal of Human Genetics 92 (4), 489-503, 2013 | 253 | 2013 |
| Point mutations in exon 1B of APC reveal gastric adenocarcinoma and proximal polyposis of the stomach as a familial adenomatous polyposis variant J Li, SL Woods, S Healey, J Beesley, X Chen, JS Lee, H Sivakumaran, ... The American Journal of Human Genetics 98 (5), 830-842, 2016 | 220 | 2016 |
| A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer L Wu, W Shi, J Long, X Guo, K Michailidou, J Beesley, MK Bolla, XO Shu, ... Nature genetics 50 (7), 968-978, 2018 | 213 | 2018 |
| Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170 AM Dunning, K Michailidou, KB Kuchenbaecker, D Thompson, JD French, ... Nature genetics 48 (4), 374-386, 2016 | 153 | 2016 |
| DNase I–hypersensitive exons colocalize with promoters and distal regulatory elements TR Mercer, SL Edwards, MB Clark, SJ Neph, H Wang, AB Stergachis, ... Nature genetics 45 (8), 852-859, 2013 | 148 | 2013 |
| Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes L Fachal, H Aschard, J Beesley, DR Barnes, J Allen, S Kar, KA Pooley, ... Nature genetics 52 (1), 56-73, 2020 | 147 | 2020 |
| Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1 KB Meyer, M O’Reilly, K Michailidou, S Carlebur, SL Edwards, JD French, ... The American Journal of Human Genetics 93 (6), 1046-1060, 2013 | 142 | 2013 |
| Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation M Ghoussaini, SL Edwards, K Michailidou, S Nord, R Cowper-Sal· lari, ... Nature communications 5 (1), 4999, 2014 | 133 | 2014 |
| The effect of intracellular iron concentration and nitrogen monoxide on Nramp2 expression and non‐transferrin‐bound iron uptake SL Wardrop, DR Richardson European journal of biochemistry 263 (1), 41-50, 1999 | 107 | 1999 |
| Interferon‐γ and lipopolysaccharide regulate the expression of Nramp2 and increase the uptake of iron from low relative molecular mass complexes by macrophages SL Wardrop, DR Richardson European Journal of Biochemistry 267 (22), 6586-6593, 2000 | 99 | 2000 |
| Five endometrial cancer risk loci identified through genome-wide association analysis THT Cheng, DJ Thompson, TA O'Mara, JN Painter, DM Glubb, S Flach, ... Nature genetics 48 (6), 667-674, 2016 | 92 | 2016 |
| Fine-scale mapping of the 5q11. 2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1 DM Glubb, MJ Maranian, K Michailidou, KA Pooley, KB Meyer, S Kar, ... The American Journal of Human Genetics 96 (1), 5-20, 2015 | 92 | 2015 |
| The role of noncoding variants in heritable disease JD French, SL Edwards Trends in Genetics 36 (11), 880-891, 2020 | 91 | 2020 |
| Long noncoding RNAs CUPID1 and CUPID2 mediate breast cancer risk at 11q13 by modulating the response to DNA damage JA Betts, MM Marjaneh, F Al-Ejeh, YC Lim, W Shi, H Sivakumaran, ... The American Journal of Human Genetics 101 (2), 255-266, 2017 | 90 | 2017 |
| Functional mechanisms underlying pleiotropic risk alleles at the 19p13. 1 breast–ovarian cancer susceptibility locus K Lawrenson, S Kar, K McCue, K Kuchenbaeker, K Michailidou, J Tyrer, ... Nature communications 7 (1), 12675, 2016 | 89 | 2016 |
| Nitrogen monoxide activates iron regulatory protein 1 RNA-binding activity by two possible mechanisms: effect on the [4Fe-4S] cluster and iron mobilization from cells SL Wardrop, RN Watts, DR Richardson Biochemistry 39 (10), 2748-2758, 2000 | 86 | 2000 |
