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Benjamin Morehouse
Benjamin Morehouse
Assistant Professor at UC Irvine, School of Biosciences, Department of Molecular Biology and
Verified email at uci.edu - Homepage
Title
Cited by
Cited by
Year
Bacterial cGAS-like enzymes synthesize diverse nucleotide signals
AT Whiteley, JB Eaglesham, CC de Oliveira Mann, BR Morehouse, ...
Nature 567 (7747), 194-199, 2019
3022019
Structure of the human cGAS–DNA complex reveals enhanced control of immune surveillance
W Zhou, AT Whiteley, CC de Oliveira Mann, BR Morehouse, RP Nowak, ...
Cell 174 (2), 300-311. e11, 2018
2792018
STING cyclic dinucleotide sensing originated in bacteria
BR Morehouse, AA Govande, A Millman, AFA Keszei, B Lowey, G Ofir, ...
Nature 586 (7829), 429-433, 2020
2692020
CBASS immunity uses CARF-related effectors to sense 3′–5′-and 2′–5′-linked cyclic oligonucleotide signals and protect bacteria from phage infection
B Lowey, AT Whiteley, AFA Keszei, BR Morehouse, IT Mathews, ...
Cell 182 (1), 38-49. e17, 2020
1512020
Cyclic CMP and cyclic UMP mediate bacterial immunity against phages
N Tal, BR Morehouse, A Millman, A Stokar-Avihail, C Avraham, ...
Cell 184 (23), 5728-5739. e16, 2021
1462021
cGAS-like receptors sense RNA and control 3′2′-cGAMP signalling in Drosophila
KM Slavik, BR Morehouse, AE Ragucci, W Zhou, X Ai, Y Chen, L Li, Z Wei, ...
Nature 597 (7874), 109-113, 2021
1142021
Viruses inhibit TIR gcADPR signaling to overcome bacterial defense
A Leavitt, E Yirmiya, G Amitai, A Lu, J Garb, BR Morehouse, SJ Hobbs, ...
Nature 611, 326–331, 2022
842022
Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity
SJ Hobbs, T Wein, A Lu, BR Morehouse, J Schnabel, A Leavitt, E Yirmiya, ...
Nature 605 (7910), 522-526, 2022
722022
Functional and Structural Characterization of a (+)-Limonene Synthase from Citrus sinensis
BR Morehouse, RP Kumar, JO Matos, SN Olsen, S Entova, DD Oprian
Biochemistry 56 (12), 1706-1715, 2017
572017
Cryo-EM structure of an active bacterial TIR–STING filament complex
BR Morehouse, MCJ Yip, AFA Keszei, NK McNamara-Bordewick, S Shao, ...
Nature 608 (7924), 803-807, 2022
472022
Structural Characterization of Early Michaelis Complexes in the Reaction Catalyzed by (+)-Limonene Synthase from Citrus sinensis Using Fluorinated Substrate …
RP Kumar, BR Morehouse, JO Matos, K Malik, H Lin, IJ Krauss, ...
Biochemistry 56 (12), 1716-1725, 2017
392017
cGLRs are a diverse family of pattern recognition receptors in innate immunity
Y Li, KM Slavik, HC Toyoda, BR Morehouse, CC de Oliveira Mann, A Elek, ...
Cell 186 (15), 3261-3276. e20, 2023
262023
Structure and monomer/dimer equilibrium for the guanylyl cyclase domain of the optogenetics protein RhoGC
RP Kumar, BR Morehouse, J Fofana, MM Trieu, DH Zhou, MO Lorenz, ...
Journal of Biological Chemistry 292 (52), 21578-21589, 2017
182017
Direct evidence of an enzyme-generated LPP intermediate in (+)-limonene synthase using a fluorinated GPP substrate analog
BR Morehouse, RP Kumar, JO Matos, Q Yu, A Bannister, K Malik, ...
ACS chemical biology 14 (9), 2035-2043, 2019
142019
cGLRs are a diverse family of pattern recognition receptors in animal innate immunity
Y Li, KM Slavik, BR Morehouse, CC de Oliveira Mann, K Mears, J Liu, ...
bioRxiv, 2023
32023
Phage defense origin of animal immunity
BR Morehouse
Current Opinion in Microbiology 73, 102295, 2023
22023
Pharmacological potential of cyclic nucleotide signaling in immunity
EMQ Ednacot, A Nabhani, DM Dinh, BR Morehouse
Pharmacology & Therapeutics, 108653, 2024
2024
An OLD protein teaches us new tricks: prokaryotic antiviral defense
EMQ Ednacot, BR Morehouse
nature communications 15 (1), 2527, 2024
2024
Say YES to single-gene lysis!
A Nabhani, BR Morehouse
Cell Host & Microbe 31 (9), 1420-1422, 2023
2023
Cyclic CMP and cyclic UMP in bacterial immunity
BR Morehouse, N Tal, NK McNamara-Bordewick, AFA Keszei, S Shao, ...
JOURNAL OF TRANSLATIONAL MEDICINE 21 (SUPPL 1), 2023
2023
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