| Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells Q Li, L Duan, JD Estes, ZM Ma, T Rourke, Y Wang, C Reilly, J Carlis, ... Nature 434 (7037), 1148-1152, 2005 | 1218 | 2005 |
| An autoinflammatory disease with deficiency of the interleukin-1–receptor antagonist I Aksentijevich, SL Masters, PJ Ferguson, P Dancey, J Frenkel, ... New England Journal of Medicine 360 (23), 2426-2437, 2009 | 1037 | 2009 |
| SARS-CoV-2 infection protects against rechallenge in rhesus macaques A Chandrashekar, J Liu, AJ Martinot, K McMahan, NB Mercado, L Peter, ... Science 369 (6505), 812-817, 2020 | 924 | 2020 |
| Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease CB Forsyth, KM Shannon, JH Kordower, RM Voigt, M Shaikh, JA Jaglin, ... PloS one 6 (12), e28032, 2011 | 879 | 2011 |
| Glycerol monolaurate prevents mucosal SIV transmission Q Li, JD Estes, PM Schlievert, L Duan, AJ Brosnahan, PJ Southern, ... Nature 458 (7241), 1034-1038, 2009 | 771 | 2009 |
| Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1 MW Melkus, JD Estes, A Padgett-Thomas, J Gatlin, PW Denton, ... Nature medicine 12 (11), 1316-1322, 2006 | 735 | 2006 |
| Immune clearance of highly pathogenic SIV infection SG Hansen, MP Jr, AB Ventura, CM Hughes, RM Gilbride, JC Ford, ... Nature 502 (7469), 100-104, 2013 | 705 | 2013 |
| Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections JD Estes, LD Harris, NR Klatt, B Tabb, S Pittaluga, M Paiardini, ... PLoS pathogens 6 (8), e1001052, 2010 | 576 | 2010 |
| B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers Y Fukazawa, R Lum, AA Okoye, H Park, K Matsuda, JY Bae, SI Hagen, ... Nature medicine 21 (2), 132-139, 2015 | 527 | 2015 |
| Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression NG Sandler, SE Bosinger, JD Estes, RTR Zhu, GK Tharp, E Boritz, ... Nature 511 (7511), 601-605, 2014 | 492 | 2014 |
| Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz BF Keele, JH Jones, KA Terio, JD Estes, RS Rudicell, ML Wilson, Y Li, ... Nature 460 (7254), 515-519, 2009 | 463 | 2009 |
| Inadequate T follicular cell help impairs B cell immunity during HIV infection RA Cubas, JC Mudd, AL Savoye, M Perreau, J Van Grevenynghe, ... Nature medicine 19 (4), 494-499, 2013 | 446 | 2013 |
| CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles YA Leong, Y Chen, HS Ong, D Wu, K Man, C Deleage, M Minnich, ... Nature immunology 17 (10), 1187-1196, 2016 | 442 | 2016 |
| Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice PW Denton, JD Estes, Z Sun, FA Othieno, BL Wei, AK Wege, DA Powell, ... PLoS medicine 5 (1), e16, 2008 | 399 | 2008 |
| Defining total-body AIDS-virus burden with implications for curative strategies JD Estes, C Kityo, F Ssali, L Swainson, KN Makamdop, GQ Del Prete, ... Nature medicine 23 (11), 1271-1276, 2017 | 388 | 2017 |
| Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections M Zeng, AJ Smith, SW Wietgrefe, PJ Southern, TW Schacker, CS Reilly, ... The Journal of clinical investigation 121 (3), 998-1008, 2011 | 382 | 2011 |
| Intrarectal transmission, systemic infection, and CD4+ T cell depletion in humanized mice infected with HIV-1 Z Sun, PW Denton, JD Estes, FA Othieno, BL Wei, AK Wege, MW Melkus, ... The Journal of experimental medicine 204 (4), 705-714, 2007 | 333 | 2007 |
| Zika viral dynamics and shedding in rhesus and cynomolgus macaques CE Osuna, SY Lim, C Deleage, BD Griffin, D Stein, LT Schroeder, ... Nature medicine 22 (12), 1448, 2016 | 324 | 2016 |
| Ad26 vaccine protects against SARS-CoV-2 severe clinical disease in hamsters LH Tostanoski, F Wegmann, AJ Martinot, C Loos, K McMahan, ... Nature medicine 26 (11), 1694-1700, 2020 | 301 | 2020 |
| Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection JD Estes, Q Li, MR Reynolds, S Wietgrefe, L Duan, T Schacker, LJ Picker, ... The Journal of infectious diseases 193 (5), 703-712, 2006 | 298 | 2006 |
