Sequence artifacts in DNA from formalin-fixed tissues: causes and strategies for minimization H Do, A Dobrovic Clinical chemistry 61 (1), 64-71, 2015 | 588 | 2015 |
GRIDSS: sensitive and specific genomic rearrangement detection using positional de Bruijn graph assembly DL Cameron, J Schröder, JS Penington, H Do, R Molania, A Dobrovic, ... Genome research 27 (12), 2050-2060, 2017 | 317 | 2017 |
Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing SQ Wong, J Li, AYC Tan, R Vedururu, JMB Pang, H Do, J Ellul, K Doig, ... BMC medical genomics 7, 1-10, 2014 | 278 | 2014 |
High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies H Do, M Krypuy, PL Mitchell, SB Fox, A Dobrovic BMC cancer 8, 1-14, 2008 | 278 | 2008 |
Loss of CDKN2A expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell
RJ Young, K Waldeck, C Martin, JH Foo, DP Cameron, L Kirby, H Do, ... Pigment cell & melanoma research 27 (4), 590-600, 2014 | 212 | 2014 |
Dramatic reduction of sequence artefacts from DNA isolated from formalin-fixed cancer biopsies by treatment with uracil-DNA glycosylase H Do, A Dobrovic Oncotarget 3 (5), 546, 2012 | 201 | 2012 |
DNA methylation biomarkers in cancer: progress towards clinical implementation T Mikeska, C Bock, H Do, A Dobrovic Expert review of molecular diagnostics 12 (5), 473-487, 2012 | 199 | 2012 |
Combination osimertinib and gefitinib in C797S and T790M EGFR-mutated nonsmall cell lung cancer S Arulananda, H Do, A Musafer, P Mitchell, A Dobrovic, T John Journal of Thoracic Oncology 12 (11), 1728-1732, 2017 | 173 | 2017 |
HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer L Da Silva, PT Simpson, CE Smart, S Cocciardi, N Waddell, A Lane, ... Breast Cancer Research 12, 1-13, 2010 | 154 | 2010 |
Reducing sequence artifacts in amplicon-based massively parallel sequencing of formalin-fixed paraffin-embedded DNA by enzymatic depletion of uracil-containing templates H Do, SQ Wong, J Li, A Dobrovic Clinical chemistry 59 (9), 1376-1383, 2013 | 129 | 2013 |
Genomic classification of serous ovarian cancer with adjacent borderline differentiates RAS pathway and TP53-mutant tumors and identifies NRAS as an oncogenic driver C Emmanuel, YE Chiew, J George, D Etemadmoghadam, MS Anglesio, ... Clinical cancer research 20 (24), 6618-6630, 2014 | 119 | 2014 |
Limited copy number-high resolution melting (LCN-HRM) enables the detection and identification by sequencing of low level mutations in cancer biopsies H Do, A Dobrovic Molecular cancer 8, 1-11, 2009 | 82 | 2009 |
Differential mechanisms of CDKN2A (p16) alteration in oral tongue squamous cell carcinomas and correlation with patient outcome AM Lim, H Do, RJ Young, SQ Wong, C Angel, M Collins, EA Takano, ... International journal of cancer 135 (4), 887-895, 2014 | 75 | 2014 |
A critical re-assessment of DNA repair gene promoter methylation in non-small cell lung carcinoma H Do, NC Wong, C Murone, T John, B Solomon, PL Mitchell, A Dobrovic Scientific reports 4 (1), 4186, 2014 | 61 | 2014 |
Detection of the transforming AKT1 mutation E17K in non-small cell lung cancer by high resolution melting H Do, B Solomon, PL Mitchell, SB Fox, A Dobrovic BMC research notes 1, 1-5, 2008 | 60 | 2008 |
Targeted-capture massively-parallel sequencing enables robust detection of clinically informative mutations from formalin-fixed tumours SQ Wong, J Li, R Salemi, KE Sheppard, H Do, RW Tothill, GA McArthur, ... Scientific Reports 3 (1), 3494, 2013 | 57 | 2013 |
BRAF InhibitorDriven Tumor Proliferation in a KRAS-Mutated Colon Carcinoma Is Not Overcome by MEK1/2 Inhibition MC Andrews, A Behren, F Chionh, J Mariadason, LJ Vella, H Do, ... Journal of Clinical Oncology 31 (35), e448-e451, 2013 | 57 | 2013 |
A multisite blinded study for the detection of BRAF mutations in formalin-fixed, paraffin-embedded malignant melanoma A Richter, F Grieu, A Carrello, B Amanuel, K Namdarian, A Rynska, ... Scientific reports 3 (1), 1659, 2013 | 45 | 2013 |
Intratumoral genetic heterogeneity in metastatic melanoma is accompanied by variation in malignant behaviors M Anaka, C Hudson, PH Lo, H Do, OL Caballero, ID Davis, A Dobrovic, ... BMC medical genomics 6, 1-13, 2013 | 40 | 2013 |
Somatic GNAQ mutation in the forme fruste of Sturge-Weber syndrome MS Hildebrand, AS Harvey, S Malone, JA Damiano, H Do, Z Ye, ... Neurology: Genetics 4 (3), e236, 2018 | 37 | 2018 |