Implication of gut microbiota metabolites in cardiovascular and metabolic diseases F Brial, A Le Lay, ME Dumas, D Gauguier Cellular and Molecular Life Sciences 75, 3977-3990, 2018 | 166 | 2018 |
Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota L Hoyles, ML Jiménez-Pranteda, J Chilloux, F Brial, A Myridakis, ... Microbiome 6 (1), 73, 2018 | 164 | 2018 |
Human and preclinical studies of the host–gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health F Brial, J Chilloux, T Nielsen, S Vieira-Silva, G Falony, P Andrikopoulos, ... Gut 70 (11), 2105-2114, 2021 | 66 | 2021 |
The natural metabolite 4-cresol improves glucose homeostasis and enhances β-cell function F Brial, F Alzaid, K Sonomura, Y Kamatani, K Meneyrol, A Le Lay, N Péan, ... Cell Reports 30 (7), 2306-2320. e5, 2020 | 43 | 2020 |
Dominant gut Prevotella copri in gastrectomised non-obese diabetic Goto–Kakizaki rats improves glucose homeostasis through enhanced FXR signalling N Péan, A Le Lay, F Brial, J Wasserscheid, C Rouch, M Vincent, ... Diabetologia 63, 1223-1235, 2020 | 38 | 2020 |
Untargeted Mass Spectrometry Lipidomics identifies correlation between serum sphingomyelins and plasma cholesterol P Zalloua, H Kadar, E Hariri, L Abi Farraj, F Brial, L Hedjazi, A Le Lay, ... Lipids in health and disease 18, 1-10, 2019 | 32 | 2019 |
Loss of hepatocyte-nuclear-factor-1α impacts on adult mouse intestinal epithelial cell growth and cell lineages differentiation CR Lussier, F Brial, SAB Roy, MJ Langlois, EF Verdu, N Rivard, ... PloS one 5 (8), e12378, 2010 | 30 | 2010 |
Mitochondrial dysfunction as a hallmark of environmental injury C Duarte-Hospital, A Tête, F Brial, L Benoit, M Koual, C Tomkiewicz, ... Cells 11 (1), 110, 2021 | 27 | 2021 |
Ghrelin Inhibition Restores Glucose Homeostasis in Hepatocyte Nuclear Factor-1α (MODY3)–Deficient Mice F Brial, CR Lussier, K Belleville, P Sarret, F Boudreau Diabetes 64 (9), 3314-3320, 2015 | 24 | 2015 |
Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota. Microbiome 6: 73 L Hoyles, ML Jimenez-Pranteda, J Chilloux, F Brial, A Myridakis, ... | 13 | 2018 |
Systems genetics of hepatic metabolome reveals octopamine as a target for non-alcoholic fatty liver disease treatment F Brial, A Le Lay, L Hedjazi, T Tsang, JF Fearnside, GW Otto, F Alzaid, ... Scientific Reports 9 (1), 3656, 2019 | 11 | 2019 |
Plasma and urine metabolomic analyses in aortic valve stenosis reveal shared and biofluid-specific changes in metabolite levels C Al Hageh, R Rahy, G Khazen, F Brial, RS Khnayzer, D Gauguier, ... PloS one 15 (11), e0242019, 2020 | 9 | 2020 |
Diet dependent impact of benzoate on diabetes and obesity in mice F Brial, F Matsuda, D Gauguier Biochimie 194, 35-42, 2022 | 7 | 2022 |
Conserved properties of genetic architecture of renal and fat transcriptomes in rat models of insulin resistance GW Otto, PJ Kaisaki, F Brial, A Le Lay, JB Cazier, R Mott, D Gauguier Disease Models & Mechanisms 12 (7), dmm038539, 2019 | 5 | 2019 |
Microbiome determinants and physiological effects of the benzoate-hippurate microbial-host co-metabolic pathway F Brial, J Chilloux, T Nielsen, S Vieira-Silva, G Falony, L Hoyles, ... BioRxiv, 2019.12. 15.876672, 2019 | 4 | 2019 |
Microbiome Inhibition of IRAK-4 by Trimethylamine Mediates Metabolic and Immune Benefits in High-Fat-Diet-induced Insulin 2 Resistance 3 J Chilloux, F Brial, A Everard, D Smyth, L Zhang, H Plovier, A Myridakis, ... crosstalk 46, 47, 2018 | 2 | 2018 |
A phenome-wide association study (PheWAS) to identify the health impacts of 4-cresol sulfate in the Nagahama Study H Ou, S Kawaguchi, K Sonomura, T Kawaguchi, S Kitada, S Yoshiji, ... Scientific Reports 13 (1), 13926, 2023 | 1 | 2023 |
Genetic Architecture of Untargeted Lipidomics in Cardiometabolic-Disease Patients Combines Strong Polygenic Control and Pleiotropy F Brial, L Hedjazi, K Sonomura, C Al Hageh, P Zalloua, F Matsuda, ... Metabolites 12 (7), 596, 2022 | 1 | 2022 |
Mass spectrometry plasma metabolomic profiling identifies metabolites associated with obesity in humans: pathophysiological role of the gut microbial metabolite indolelactic … F Brial, K Sonomura, J Russick, TA Sato, F Matsuda, D Gauguier, ... Precision Nutrition 1 (1), 10.1097, 2022 | 1 | 2022 |
Microbiome inhibition of IRAK-4 by trimethylamine mediates metabolic and immune benefits in high fat diet-induced insulin resistance ME Dumas, J Chilloux, A Myridakis, L Hoyles, A Everard, H Plovier, ... Diabetologia 61, S267-S268, 2018 | 1 | 2018 |