Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers E Lim, F Vaillant, D Wu, NC Forrest, B Pal, AH Hart, ML Asselin-Labat, ... Nature medicine 15 (8), 907-913, 2009 | 1683 | 2009 |
Control of mammary stem cell function by steroid hormone signalling ML Asselin-Labat, F Vaillant, JM Sheridan, B Pal, D Wu, ER Simpson, ... Nature 465 (7299), 798-802, 2010 | 810 | 2010 |
Notch signaling regulates mammary stem cell function and luminal cell-fate commitment T Bouras, B Pal, F Vaillant, G Harburg, ML Asselin-Labat, SR Oakes, ... Cell stem cell 3 (4), 429-441, 2008 | 546 | 2008 |
Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways E Lim, D Wu, B Pal, T Bouras, ML Asselin-Labat, F Vaillant, H Yagita, ... Breast Cancer Research 12, 1-14, 2010 | 492 | 2010 |
Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells M Rigau, S Ostrouska, TS Fulford, DN Johnson, K Woods, Z Ruan, ... Science 367 (6478), eaay5516, 2020 | 386 | 2020 |
Targeting BCL-2 with the BH3 mimetic ABT-199 in estrogen receptor-positive breast cancer F Vaillant, D Merino, L Lee, K Breslin, B Pal, ME Ritchie, GK Smyth, ... Cancer cell 24 (1), 120-129, 2013 | 315 | 2013 |
RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers E Nolan, F Vaillant, D Branstetter, B Pal, G Giner, L Whitehead, SW Lok, ... Nature medicine 22 (8), 933-939, 2016 | 287 | 2016 |
A single‐cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast B Pal, Y Chen, F Vaillant, BD Capaldo, R Joyce, X Song, VL Bryant, ... The EMBO journal 40 (11), e107333, 2021 | 267 | 2021 |
Taurine deficiency as a driver of aging P Singh, K Gollapalli, S Mangiola, D Schranner, MA Yusuf, M Chamoli, ... Science 380 (6649), eabn9257, 2023 | 215 | 2023 |
Construction of developmental lineage relationships in the mouse mammary gland by single-cell RNA profiling B Pal, Y Chen, F Vaillant, P Jamieson, L Gordon, AC Rios, S Wilcox, N Fu, ... Nature communications 8 (1), 1627, 2017 | 198 | 2017 |
Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer D Merino, JR Whittle, F Vaillant, A Serrano, JN Gong, G Giner, ... Science translational medicine 9 (401), eaam7049, 2017 | 197 | 2017 |
Intraclonal plasticity in mammary tumors revealed through large-scale single-cell resolution 3D imaging AC Rios, BD Capaldo, F Vaillant, B Pal, R van Ineveld, CA Dawson, ... Cancer cell 35 (4), 618-632. e6, 2019 | 160 | 2019 |
Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2 B Pal, T Bouras, W Shi, F Vaillant, JM Sheridan, N Fu, K Breslin, K Jiang, ... Cell reports 3 (2), 411-426, 2013 | 160 | 2013 |
Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling CA Dawson, B Pal, F Vaillant, LC Gandolfo, Z Liu, C Bleriot, F Ginhoux, ... Nature cell biology 22 (5), 546-558, 2020 | 159 | 2020 |
A phase Ib dose-escalation and expansion study of the BCL2 inhibitor venetoclax combined with tamoxifen in ER and BCL2positive metastatic breast cancer SW Lok, JR Whittle, F Vaillant, CE Teh, LL Lo, AN Policheni, ART Bergin, ... Cancer discovery 9 (3), 354-369, 2019 | 144 | 2019 |
Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer D Merino, TS Weber, A Serrano, F Vaillant, K Liu, B Pal, L Di Stefano, ... Nature communications 10 (1), 766, 2019 | 140 | 2019 |
Identification of quiescent and spatially restricted mammary stem cells that are hormone responsive NY Fu, AC Rios, B Pal, CW Law, P Jamieson, R Liu, F Vaillant, F Jackling, ... Nature cell biology 19 (3), 164-176, 2017 | 133 | 2017 |
Essential role for a novel population of binucleated mammary epithelial cells in lactation AC Rios, NY Fu, PR Jamieson, B Pal, L Whitehead, KR Nicholas, ... Nature communications 7 (1), 11400, 2016 | 104 | 2016 |
Differential methylation analysis of reduced representation bisulfite sequencing experiments using edgeR Y Chen, B Pal, JE Visvader, GK Smyth F1000Research 6, 2055, 2018 | 103 | 2018 |
EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival NY Fu, AC Rios, B Pal, R Soetanto, ATL Lun, K Liu, T Beck, SA Best, ... Nature Cell Biology 17 (4), 365-375, 2015 | 93 | 2015 |