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Blake T Aftab, PhD
Blake T Aftab, PhD
Chief Scientific Officer @ Adicet Bio
Verified email at aftab.com
Title
Cited by
Cited by
Year
Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM
TV Lanz, RC Brewer, PP Ho, JS Moon, KM Jude, D Fernandez, ...
Nature 603 (7900), 321-327, 2022
4682022
Itraconazole and arsenic trioxide inhibit Hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists
J Kim, BT Aftab, JY Tang, D Kim, AH Lee, M Rezaee, J Kim, B Chen, ...
Cancer cell 23 (1), 23-34, 2013
3972013
Targeting the AAA ATPase p97 as an approach to treat cancer through disruption of protein homeostasis
DJ Anderson, R Le Moigne, S Djakovic, B Kumar, J Rice, S Wong, J Wang, ...
Cancer cell 28 (5), 653-665, 2015
3862015
Epstein–Barr virus in multiple sclerosis: theory and emerging immunotherapies
A Bar-Or, MP Pender, R Khanna, L Steinman, HP Hartung, T Maniar, ...
Trends in molecular medicine 26 (3), 296-310, 2020
2622020
Itraconazole inhibits angiogenesis and tumor growth in non–small cell lung cancer
BT Aftab, I Dobromilskaya, JO Liu, CM Rudin
Cancer research 71 (21), 6764-6772, 2011
2022011
Phase 2 study of pemetrexed and itraconazole as second-line therapy for metastatic nonsquamous non–small-cell lung cancer
CM Rudin, JR Brahmer, RA Juergens, CL Hann, DS Ettinger, R Sebree, ...
Journal of Thoracic Oncology 8 (5), 619-623, 2013
1692013
Epstein-Barr virus–specific T cell therapy for progressive multiple sclerosis
MP Pender, PA Csurhes, C Smith, NL Douglas, MA Neller, KK Matthews, ...
JCI insight 3 (22), 2018
1422018
Validation of the Hsp70–Bag3 protein–protein interaction as a potential therapeutic target in cancer
X Li, T Colvin, JN Rauch, D Acosta-Alvear, M Kampmann, B Dunyak, ...
Molecular cancer therapeutics 14 (3), 642-648, 2015
1342015
The p97 inhibitor CB-5083 is a unique disrupter of protein homeostasis in models of multiple myeloma
R Le Moigne, BT Aftab, S Djakovic, E Dhimolea, E Valle, M Murnane, ...
Molecular cancer therapeutics 16 (11), 2375-2386, 2017
1092017
Molecular signature of Epstein-Barr virus infection in MS brain lesions
MA Moreno, N Or-Geva, BT Aftab, R Khanna, E Croze, L Steinman, ...
Neurology: Neuroimmunology & Neuroinflammation 5 (4), e466, 2018
992018
Bridging the gap between preclinical and clinical studies using pharmacokinetic–pharmacodynamic modeling: an analysis of GDC-0973, a MEK inhibitor
H Wong, L Vernillet, A Peterson, JA Ware, L Lee, JF Martini, P Yu, C Li, ...
Clinical Cancer Research 18 (11), 3090-3099, 2012
962012
Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells
DW Sherbenou, BT Aftab, Y Su, CR Behrens, A Wiita, AC Logan, ...
The Journal of clinical investigation 126 (12), 4640-4653, 2016
942016
Off-the-shelf Vδ1 gamma delta T cells engineered with glypican-3 (GPC-3)-specific chimeric antigen receptor (CAR) and soluble IL-15 display robust antitumor efficacy against …
A Makkouk, XC Yang, T Barca, A Lucas, M Turkoz, JTS Wong, ...
Journal for immunotherapy of cancer 9 (12), 2021
912021
A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling (NanoHHI) bypasses secondary mutational resistance to Smoothened antagonists
V Chenna, C Hu, D Pramanik, BT Aftab, C Karikari, NR Campbell, ...
Molecular cancer therapeutics 11 (1), 165-173, 2012
892012
Itraconazole side chain analogues: structure–activity relationship studies for inhibition of endothelial cell proliferation, vascular endothelial growth factor receptor 2 …
W Shi, BA Nacev, BT Aftab, S Head, CM Rudin, JO Liu
Journal of medicinal chemistry 54 (20), 7363-7374, 2011
762011
Compositions comprising anti-CD38 antibodies and lenalidomide
BC Hann, B Tomkinson, TG Martin III, BT Aftab
US Patent 10,342,869, 2019
532019
Allogeneic CD20‐targeted γδ T cells exhibit innate and adaptive antitumor activities in preclinical B‐cell lymphoma models
KP Nishimoto, T Barca, A Azameera, A Makkouk, JM Romero, L Bai, ...
Clinical & Translational Immunology 11 (2), e1373, 2022
512022
Genome-wide association study identifies variants at 16p13 associated with survival in multiple myeloma patients
E Ziv, E Dean, D Hu, A Martino, D Serie, K Curtin, D Campa, B Aftab, ...
Nature communications 6 (1), 7539, 2015
492015
Genome-wide association study identifies variants at 16p13 associated with survival in multiple myeloma patients
E Ziv, E Dean, D Hu, A Martino, D Serie, K Curtin, D Campa, B Aftab, ...
Nature communications 6 (1), 7539, 2015
492015
Hedgehog pathway inhibition radiosensitizes non-small cell lung cancers
J Zeng, K Aziz, ST Chettiar, BT Aftab, M Armour, R Gajula, N Gandhi, ...
International Journal of Radiation Oncology* Biology* Physics 86 (1), 143-149, 2013
482013
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