Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA BF Luisi, WX Xu, Z Otwinowski, LP Freedman, KR Yamamoto, PB Sigler Nature 352 (6335), 497-505, 1991 | 1954 | 1991 |
The economics of reproducibility in preclinical research LP Freedman, IM Cockburn, TS Simcoe PLoS biology 13 (6), e1002165, 2015 | 1161 | 2015 |
Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937. M Liu, MH Lee, M Cohen, M Bommakanti, LP Freedman Genes & development 10 (2), 142-153, 1996 | 1117 | 1996 |
Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex C Rachez, BD Lemon, Z Suldan, V Bromleigh, M Gamble, AM Näär, ... Nature 398 (6730), 824-828, 1999 | 888 | 1999 |
Solution structure of the glucocorticoid receptor DNA-binding domain T Härd, E Kellenbach, R Boelens, BA Maler, K Dahlman, LP Freedman, ... Science 249 (4965), 157-160, 1990 | 750 | 1990 |
The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain LP Freedman, BF Luisi, ZR Korszun, R Basavappa, PB Sigler, ... Nature 334 (6182), 543-546, 1988 | 697 | 1988 |
Increasing the complexity of coactivation in nuclear receptor signaling LP Freedman Cell 97 (1), 5-8, 1999 | 538 | 1999 |
Transcriptional Repression of the Interleukin-2 Gene by Vitamin D3: Direct Inhibition of NFATp/AP-1 Complex Formation by a Nuclear Hormone Receptor I Alroy, TL Towers, LP Freedman Molecular and cellular biology 15 (10), 5789-5799, 1995 | 528 | 1995 |
A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system C Rachez, Z Suldan, J Ward, CPB Chang, D Burakov, ... Genes & development 12 (12), 1787-1800, 1998 | 505 | 1998 |
Anatomy of the steroid receptor zinc finger region LP Freedman Endocrine reviews 13 (2), 129-145, 1992 | 483 | 1992 |
Mechanisms of gene regulation by vitamin D3 receptor: a network of coactivator interactions C Rachez, LP Freedman Gene 246 (1-2), 9-21, 2000 | 425 | 2000 |
Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival SA Krum, GA Miranda‐Carboni, PV Hauschka, JS Carroll, TF Lane, ... The EMBO journal 27 (3), 535-545, 2008 | 420 | 2008 |
Transcriptional activation of the human p21WAF1/CIP1 gene by retinoic acid receptor: correlation with retinoid induction of U937 cell differentiation M Liu, A Iavarone, LP Freedman Journal of Biological Chemistry 271 (49), 31723-31728, 1996 | 386 | 1996 |
1, 25-dihydroxyvitamin D3 inhibits IFN-γ and IL-4 levels during in vitro polarization of primary murine CD4+ T cells TP Staeva-Vieira, LP Freedman The Journal of Immunology 168 (3), 1181-1189, 2002 | 383 | 2002 |
Repression of transcription of the p27Kip1 cyclin-dependent kinase inhibitor gene by c-Myc W Yang, J Shen, M Wu, M Arsura, M FitzGerald, Z Suldan, DW Kim, ... Oncogene 20 (14), 1688-1702, 2001 | 381 | 2001 |
Differential regulation of glucocorticoid receptor transcriptional activation via AF‐1‐associated proteins AB Hittelman, D Burakov, JA Iñiguez‐Lluhí, LP Freedman, MJ Garabedian The EMBO journal, 1999 | 365 | 1999 |
Mediator complexes and transcription C Rachez, LP Freedman Current opinion in cell biology 13 (3), 274-280, 2001 | 360 | 2001 |
A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II HM Bourbon, A Aguilera, AZ Ansari, FJ Asturias, AJ Berk, S Bjorklund, ... Molecular cell 14 (5), 553-557, 2004 | 350 | 2004 |
Signaling by estrogens BJ Cheskis, JG Greger, S Nagpal, LP Freedman Journal of cellular physiology 213 (3), 610-617, 2007 | 305 | 2007 |
Mutations in the glucocorticoid receptor zinc finger region that distinguish interdigitated DNA binding and transcriptional enhancement activities. M Schena, LP Freedman, KR Yamamoto Genes & development 3 (10), 1590-1601, 1989 | 275 | 1989 |