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Karen E Inouye
Karen E Inouye
Research Scientist, Harvard TH Chan School of Public Health
Verified email at hsph.harvard.edu
Title
Cited by
Cited by
Year
TLR4 links innate immunity and fatty acid–induced insulin resistance
H Shi, MV Kokoeva, K Inouye, I Tzameli, H Yin, JS Flier
The Journal of clinical investigation 116 (11), 3015-3025, 2006
43082006
Novel role of PKR in inflammasome activation and HMGB1 release
B Lu, T Nakamura, K Inouye, J Li, Y Tang, P Lundbäck, SI Valdes-Ferrer, ...
Nature 488 (7413), 670-674, 2012
8232012
Chronic enrichment of hepatic endoplasmic reticulum–mitochondria contact leads to mitochondrial dysfunction in obesity
AP Arruda, BM Pers, G Parlakgül, E Güney, K Inouye, GS Hotamisligil
Nature medicine 20 (12), 1427-1435, 2014
6192014
Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue
KE Inouye, H Shi, JK Howard, CH Daly, GM Lord, BJ Rollins, JS Flier
Diabetes 56 (9), 2242-2250, 2007
2942007
Adipocyte lipid chaperone AP2 is a secreted adipokine regulating hepatic glucose production
H Cao, M Sekiya, ME Ertunc, MF Burak, JR Mayers, A White, K Inouye, ...
Cell metabolism 17 (5), 768-778, 2013
2602013
Diabetes and the hypothalamo-pituitary-adrenal (HPA) axis.
O Chan, K Inouye, MC Riddell, M Vranic, SG Matthews
Minerva endocrinologica 28 (2), 87-102, 2003
2402003
The short-chain fatty acid propionate increases glucagon and FABP4 production, impairing insulin action in mice and humans
A Tirosh, ES Calay, G Tuncman, KC Claiborn, KE Inouye, K Eguchi, ...
Science translational medicine 11 (489), eaav0120, 2019
2232019
A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use
S Liu, JD Brown, KJ Stanya, E Homan, M Leidl, K Inouye, P Bhargava, ...
Nature 502 (7472), 550-554, 2013
2142013
Direct control of hepatic glucose production by interleukin-13 in mice
KJ Stanya, D Jacobi, S Liu, P Bhargava, L Dai, MR Gangl, K Inouye, ...
The Journal of clinical investigation 123 (1), 2012
1692012
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
A Bartelt, SB Widenmaier, C Schlein, K Johann, RLS Goncalves, K Eguchi, ...
Nature medicine 24 (3), 292-303, 2018
1652018
Hyperactivation of the hypothalamo-pituitary-adrenocortical axis in streptozotocin-diabetes is associated with reduced stress responsiveness and decreased pituitary and adrenal …
O Chan, K Inouye, M Vranic, SG Matthews
Endocrinology 143 (5), 1761-1768, 2002
1372002
Overexpression of suppressor of cytokine signaling 3 in adipose tissue causes local but not systemic insulin resistance
H Shi, B Cave, K Inouye, C Bjørbæk, JS Flier
Diabetes 55 (3), 699-707, 2006
1352006
Molecular regulation of the hypothalamo-pituitary-adrenal axis in streptozotocin-induced diabetes: effects of insulin treatment
O Chan, S Chan, K Inouye, M Vranic, SG Matthews
Endocrinology 142 (11), 4872-4879, 2001
1352001
Diabetes impairs hypothalamo-pituitary-adrenal (HPA) responses to hypoglycemia, and insulin treatment normalizes HPA but not epinephrine responses
O Chan, S Chan, K Inouye, K Shum, SG Matthews, M Vranic
Diabetes 51 (6), 1681-1689, 2002
1122002
Insulin alone increases hypothalamo-pituitary-adrenal activity, and diabetes lowers peak stress responses
O Chan, K Inouye, E Akirav, E Park, MC Riddell, M Vranic, SG Matthews
Endocrinology 146 (3), 1382-1390, 2005
962005
Development of a therapeutic monoclonal antibody that targets secreted fatty acid–binding protein aP2 to treat type 2 diabetes
MF Burak, KE Inouye, A White, A Lee, G Tuncman, ES Calay, M Sekiya, ...
Science translational medicine 7 (319), 319ra205-319ra205, 2015
942015
The role of adipocyte XBP1 in metabolic regulation during lactation
MF Gregor, ES Misch, L Yang, S Hummasti, KE Inouye, AH Lee, B Bierie, ...
Cell reports 3 (5), 1430-1439, 2013
932013
Increased oxidative phosphorylation in response to acute and chronic DNA damage
LE Brace, SC Vose, K Stanya, RM Gathungu, VR Marur, A Longchamp, ...
npj Aging and Mechanisms of Disease 2 (1), 1-11, 2016
792016
Hyperglycemia does not increase basal hypothalamo-pituitary-adrenal activity in diabetes but it does impair the HPA response to insulin-induced hypoglycemia
O Chan, K Inouye, EM Akirav, E Park, MC Riddell, SG Matthews, M Vranic
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2005
662005
Regulation of liver subcellular architecture controls metabolic homeostasis
G Parlakgül, AP Arruda, S Pang, E Cagampan, N Min, E Güney, GY Lee, ...
Nature 603 (7902), 736-742, 2022
582022
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