Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation KJ Ewer, GA O’Hara, CJA Duncan, KA Collins, SH Sheehy, ... Nature communications 4 (1), 2836, 2013 | 371 | 2013 |
Evaluation of the efficacy of ChAd63-MVA vectored vaccines expressing circumsporozoite protein and ME-TRAP against controlled human malaria infection in malaria-naive individuals SH Hodgson, KJ Ewer, CM Bliss, NJ Edwards, T Rampling, ... The Journal of infectious diseases 211 (7), 1076-1086, 2015 | 162 | 2015 |
Development and validation of serological markers for detecting recent Plasmodium vivax infection RJ Longley, MT White, E Takashima, J Brewster, M Morita, M Harbers, ... Nature medicine 26 (5), 741-749, 2020 | 116 | 2020 |
Optimising controlled human malaria infection studies using cryopreserved P. falciparum parasites administered by needle and syringe SH Sheehy, AJ Spencer, AD Douglas, BKL Sim, RJ Longley, NJ Edwards, ... PloS one 8 (6), e65960, 2013 | 116 | 2013 |
Multiplex assays for the identification of serological signatures of SARS-CoV-2 infection: an antibody-based diagnostic and machine learning study J Rosado, S Pelleau, C Cockram, SH Merkling, N Nekkab, C Demeret, ... The Lancet Microbe 2 (2), e60-e69, 2021 | 94 | 2021 |
Host resistance to malaria: using mouse models to explore the host response R Longley, C Smith, A Fortin, J Berghout, B McMorran, G Burgio, S Foote, ... Mammalian Genome 22, 32-42, 2011 | 68 | 2011 |
Insights into the naturally acquired immune response to Plasmodium vivax malaria RJ Longley, J Sattabongkot, IVO Mueller Parasitology 143 (2), 154-170, 2016 | 67 | 2016 |
Comparative assessment of vaccine vectors encoding ten malaria antigens identifies two protective liver-stage candidates RJ Longley, AM Salman, MG Cottingham, K Ewer, CJ Janse, SM Khan, ... Scientific reports 5 (1), 11820, 2015 | 67 | 2015 |
Naturally acquired antibody responses to more than 300 Plasmodium vivax proteins in three geographic regions RJ Longley, MT White, E Takashima, M Morita, BN Kanoi, ... PLoS neglected tropical diseases 11 (9), e0005888, 2017 | 59 | 2017 |
Acquisition and longevity of antibodies to Plasmodium vivax preerythrocytic antigens in Western Thailand RJ Longley, A Reyes-Sandoval, E Montoya-Díaz, S Dunachie, ... Clinical and Vaccine Immunology 23 (2), 117-124, 2016 | 57 | 2016 |
Enhanced vaccine-induced CD8+ T cell responses to malaria antigen ME-TRAP by fusion to MHC class ii invariant chain AJ Spencer, MG Cottingham, JA Jenks, RJ Longley, S Capone, S Colloca, ... PloS one 9 (6), e100538, 2014 | 52 | 2014 |
Plasmodium vivax and Plasmodium falciparum infection dynamics: re-infections, recrudescences and relapses MT White, S Karl, C Koepfli, RJ Longley, NE Hofmann, R Wampfler, ... Malaria journal 17, 1-15, 2018 | 51 | 2018 |
Mixed vector immunization with recombinant adenovirus and MVA can improve vaccine efficacy while decreasing antivector immunity A Reyes-Sandoval, CS Rollier, A Milicic, K Bauza, MG Cottingham, ... Molecular therapy 20 (8), 1633-1647, 2012 | 45 | 2012 |
Asymptomatic Plasmodium vivax infections induce robust IgG responses to multiple blood-stage proteins in a low-transmission region of western Thailand RJ Longley, CT França, MT White, C Kumpitak, P Sa-Angchai, ... Malaria journal 16, 1-13, 2017 | 44 | 2017 |
Serological signatures of SARS-CoV-2 infection: implications for antibody-based diagnostics J Rosado, S Pelleau, C Cockram, S Hélène Merkling, N Nekkab, ... MedRxiv, 2020.05. 07.20093963, 2020 | 33 | 2020 |
Malaria vaccines: identifying Plasmodium falciparum liver-stage targets RJ Longley, AVS Hill, AJ Spencer Frontiers in microbiology 6, 965, 2015 | 33 | 2015 |
Development of an In Vitro Assay and Demonstration of Plasmodium berghei Liver-Stage Inhibition by TRAP-Specific CD8+ T Cells RJ Longley, K Bauza, KJ Ewer, AVS Hill, AJ Spencer PloS one 10 (3), e0119880, 2015 | 28 | 2015 |
The threshold of protection from liver-stage malaria relies on a fine balance between the number of infected hepatocytes and effector CD8+ T cells present in the liver AJ Spencer, RJ Longley, A Gola, M Ulaszewska, T Lambe, AVS Hill The Journal of Immunology 198 (5), 2006-2016, 2017 | 25 | 2017 |
Assessment of the Plasmodium falciparum preerythrocytic antigen UIS3 as a potential candidate for a malaria vaccine RJ Longley, BR Halbroth, AM Salman, KJ Ewer, SH Hodgson, CJ Janse, ... Infection and Immunity 85 (3), 10.1128/iai. 00641-16, 2017 | 24 | 2017 |
Changes in serological immunology measures in UK and Kenyan adults post-controlled human malaria infection SH Hodgson, D Llewellyn, SE Silk, KH Milne, SC Elias, K Miura, ... Frontiers in microbiology 7, 1604, 2016 | 24 | 2016 |