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Brian W Simons
Brian W Simons
Verified email at bcm.edu
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Year
Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation
CS Schneider, Q Xu, NJ Boylan, J Chisholm, BC Tang, BS Schuster, ...
Science advances 3 (4), e1601556, 2017
2632017
Animal models of human prostate cancer: the consensus report of the New York meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee
M Ittmann, J Huang, E Radaelli, P Martin, S Signoretti, R Sullivan, ...
Cancer research 73 (9), 2718-2736, 2013
2582013
Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to …
UD Kahlert, D Maciaczyk, S Doostkam, BA Orr, B Simons, T Bogiel, ...
Cancer letters 325 (1), 42-53, 2012
2462012
Androgen-induced programs for prostate epithelial growth and invasion arise in embryogenesis and are reactivated in cancer
EM Schaeffer, L Marchionni, Z Huang, B Simons, A Blackman, W Yu, ...
Oncogene 27 (57), 7180-7191, 2008
1972008
Targeting the EMT transcription factor TWIST1 overcomes resistance to EGFR inhibitors in EGFR-mutant non-small-cell lung cancer
ZA Yochum, J Cades, H Wang, S Chatterjee, BW Simons, JP O’Brien, ...
Oncogene 38 (5), 656-670, 2019
1622019
Correlation of B7-H3 with androgen receptor, immune pathways and poor outcome in prostate cancer: an expression-based analysis
B Benzon, SG Zhao, MC Haffner, M Takhar, N Erho, K Yousefi, P Hurley, ...
Prostate cancer and prostatic diseases 20 (1), 28-35, 2017
1382017
Nanoparticle interactions with immune cells dominate tumor retention and induce T cell–mediated tumor suppression in models of breast cancer
P Korangath, JD Barnett, A Sharma, ET Henderson, J Stewart, SH Yu, ...
Science advances 6 (13), eaay1601, 2020
1292020
An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer
S Ling, X Chang, L Schultz, TK Lee, A Chaux, L Marchionni, GJ Netto, ...
Cancer research 71 (11), 3812-3821, 2011
1282011
Notch signaling in prostate cancer: a moving target
FLF Carvalho, BW Simons, CG Eberhart, DM Berman
The Prostate 74 (9), 933-945, 2014
1172014
TWIST1-WDR5-Hottip Regulates Hoxa9 Chromatin to Facilitate Prostate Cancer Metastasis
R Malek, RP Gajula, RD Williams, B Nghiem, BW Simons, K Nugent, ...
Cancer research 77 (12), 3181-3193, 2017
1152017
Vaginal delivery of paclitaxel via nanoparticles with non‐mucoadhesive surfaces suppresses cervical tumor growth
M Yang, T Yu, YY Wang, SK Lai, Q Zeng, B Miao, BC Tang, BW Simons, ...
Advanced healthcare materials 3 (7), 1044-1052, 2014
1072014
Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells
JE Ohm, P Mali, L Van Neste, DM Berman, L Liang, K Pandiyan, ...
Cancer research 70 (19), 7662-7673, 2010
982010
A human prostatic bacterial isolate alters the prostatic microenvironment and accelerates prostate cancer progression
BW Simons, NM Durham, TC Bruno, JF Grosso, AJ Schaeffer, AE Ross, ...
The Journal of pathology 235 (3), 478-489, 2015
862015
Sox9 is required for prostate development and prostate cancer initiation
Z Huang, PJ Hurley, BW Simons, L Marchionni, DM Berman, AE Ross, ...
Oncotarget 3 (6), 651, 2012
652012
Enhancement of airway gene transfer by DNA nanoparticles using a pH-responsive block copolymer of polyethylene glycol and poly-L-lysine
NJ Boylan, AJ Kim, JS Suk, P Adstamongkonkul, BW Simons, SK Lai, ...
Biomaterials 33 (7), 2361-2371, 2012
612012
Secreted protein, acidic and rich in cysteine-like 1 (SPARCL1) is down regulated in aggressive prostate cancers and is prognostic for poor clinical outcome
PJ Hurley, L Marchionni, BW Simons, AE Ross, SB Peskoe, RM Miller, ...
Proceedings of the National Academy of Sciences 109 (37), 14977-14982, 2012
602012
A potential tumor suppressor role for Hic1 in breast cancer through transcriptional repression of ephrin-A1
W Zhang, X Zeng, KJ Briggs, R Beaty, B Simons, RW Chiu Yen, MA Tyler, ...
Oncogene 29 (17), 2467-2476, 2010
602010
Wnt signaling though beta-catenin is required for prostate lineage specification
BW Simons, PJ Hurley, Z Huang, AE Ross, R Miller, L Marchionni, ...
Developmental biology 371 (2), 246-255, 2012
592012
O-GlcNAcylation is required for mutant KRAS-induced lung tumorigenesis
K Taparra, H Wang, R Malek, A Lafargue, MA Barbhuiya, X Wang, ...
The Journal of clinical investigation 128 (11), 4924-4937, 2019
572019
Asporin restricts mesenchymal stromal cell differentiation, alters the tumor microenvironment, and drives metastatic progression
RM Hughes, BW Simons, H Khan, R Miller, V Kugler, S Torquato, ...
Cancer research 79 (14), 3636-3650, 2019
552019
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