Activation of innate immune antiviral responses by Nod2 A Sabbah, TH Chang, R Harnack, V Frohlich, K Tominaga, PH Dube, ... Nature immunology 10 (10), 1073-1080, 2009 | 915 | 2009 |
Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against Mpro and cathepsin L MD Sacco, C Ma, P Lagarias, A Gao, JA Townsend, X Meng, P Dube, ... Science Advances 6 (50), eabe0751, 2020 | 340 | 2020 |
Pore-forming toxins induce macrophage necroptosis during acute bacterial pneumonia N González-Juarbe, RP Gilley, CA Hinojosa, KM Bradley, A Kamei, G Gao, ... PLoS pathogens 11 (12), e1005337, 2015 | 228 | 2015 |
Mycoplasma pneumoniae CARDS Toxin Induces Pulmonary Eosinophilic and Lymphocytic Inflammation JL Medina, JJ Coalson, EG Brooks, VT Winter, A Chaparro, MFR Principe, ... American journal of respiratory cell and molecular biology 46 (6), 815-822, 2012 | 146 | 2012 |
Mutation of Pro-258 in transmembrane domain 6 constitutively activates the G protein-coupled alpha-factor receptor. JB Konopka, SM Margarit, P Dube Proceedings of the National Academy of Sciences 93 (13), 6764-6769, 1996 | 143 | 1996 |
A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum X Zhang, L Gao, L Lei, Y Zhong, P Dube, MT Berton, B Arulanandam, ... The Journal of Immunology 183 (2), 1291-1300, 2009 | 130 | 2009 |
Severe pneumococcal pneumonia causes acute cardiac toxicity and subsequent cardiac remodeling LF Reyes, MI Restrepo, CA Hinojosa, NJ Soni, A Anzueto, BL Babu, ... American Journal of Respiratory and Critical Care Medicine 196 (5), 609-620, 2017 | 123 | 2017 |
Analysis of Pulmonary Inflammation and Function in the Mouse and Baboon after Exposure to Mycoplasma pneumoniae CARDS Toxin RD Hardy, JJ Coalson, J Peters, A Chaparro, C Techasaensiri, ... PloS one 4 (10), e7562, 2009 | 122 | 2009 |
Delayed inflammatory response to primary pneumonic plague occurs in both outbred and inbred mice SS Bubeck, AM Cantwell, PH Dube Infection and immunity 75 (2), 697-705, 2007 | 120 | 2007 |
Pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia N González-Juarbe, KM Bradley, AT Shenoy, RP Gilley, LF Reyes, ... Cell Death & Differentiation 24 (5), 917-928, 2017 | 96 | 2017 |
Protective Role of Interleukin-6 during Yersinia enterocolitica Infection Is Mediated through the Modulation of Inflammatory Cytokines PH Dube, SA Handley, J Lewis, VL Miller Infection and immunity 72 (6), 3561-3570, 2004 | 88 | 2004 |
A role for IL-1α in inducing pathologic inflammation during bacterial infection PH Dube, PA Revell, DD Chaplin, RG Lorenz, VL Miller Proceedings of the National Academy of Sciences 98 (19), 10880-10885, 2001 | 88 | 2001 |
Integrin-mediated first signal for inflammasome activation in intestinal epithelial cells J Thinwa, JA Segovia, S Bose, PH Dube The Journal of Immunology 193 (3), 1373-1382, 2014 | 86 | 2014 |
Yersinia pestis CO92ΔyopH Is a Potent Live, Attenuated Plague Vaccine SS Bubeck, PH Dube Clinical and Vaccine Immunology 14 (9), 1235-1238, 2007 | 77 | 2007 |
Identification of a polar region in transmembrane domain 6 that regulates the function of the G protein-coupled α-factor receptor P Dube, JB Konopka Molecular and cellular biology 18 (12), 7205-7215, 1998 | 66 | 1998 |
Infiltrated macrophages die of pneumolysin-mediated necroptosis following pneumococcal myocardial invasion RP Gilley, N González-Juarbe, AT Shenoy, LF Reyes, PH Dube, ... Infection and immunity 84 (5), 1457-1469, 2016 | 65 | 2016 |
Interaction of Yersinia with the Gut: Mechanisms of Pathogenesis and Immune Evasion P Dube Molecular mechanisms of bacterial infection via the gut, 61-91, 2009 | 64 | 2009 |
Histamine signaling through the H2 receptor in the Peyer’s patch is important for controlling Yersinia enterocolitica infection SA Handley, PH Dube, VL Miller Proceedings of the National Academy of Sciences 103 (24), 9268-9273, 2006 | 62 | 2006 |
Interaction between transmembrane domains five and six of the α-factor receptor P Dube, A DeCostanzo, JB Konopka Journal of Biological Chemistry 275 (34), 26492-26499, 2000 | 57 | 2000 |
Characterization of Oral Yersinia enterocolitica Infection in Three Different Strains of Inbred Mice SA Handley, PH Dube, PA Revell, VL Miller Infection and immunity 72 (3), 1645-1656, 2004 | 53 | 2004 |