Microwave assisted organic reactions S Caddick Tetrahedron 51 (38), 10403-10432, 1995 | 2254 | 1995 |
Microwave enhanced synthesis S Caddick, R Fitzmaurice Tetrahedron 65 (17), 3325-3355, 2009 | 492 | 2009 |
Protein modification, bioconjugation, and disulfide bridging using bromomaleimides MEB Smith, FF Schumacher, CP Ryan, LM Tedaldi, D Papaioannou, ... Journal of the American Chemical Society 132 (6), 1960-1965, 2010 | 438 | 2010 |
Recent advances in the construction of antibody–drug conjugates V Chudasama, A Maruani, S Caddick Nature chemistry 8 (2), 114-119, 2016 | 363 | 2016 |
Dynamic resolutions in asymmetric synthesis S Caddick, K Jenkins Chemical Society Reviews 25 (6), 447-456, 1996 | 283 | 1996 |
A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy A Maruani, MEB Smith, E Miranda, KA Chester, V Chudasama, S Caddick Nature communications 6 (1), 6645, 2015 | 265 | 2015 |
Direct synthesis of sulfonamides and activated sulfonate esters from sulfonic acids S Caddick, JD Wilden, DB Judd Journal of the American Chemical Society 126 (4), 1024-1025, 2004 | 227 | 2004 |
A generic approach for the catalytic reduction of nitriles S Caddick, DB Judd, AK de K Lewis, MT Reich, MRV Williams Tetrahedron 59 (29), 5417-5423, 2003 | 202 | 2003 |
Hydroacylation of α, β-unsaturated esters via aerobic C–H activation V Chudasama, RJ Fitzmaurice, S Caddick Nature chemistry 2 (7), 592-596, 2010 | 194 | 2010 |
Unusual reactivity of a nickel N-heterocyclic carbene complex: tert-butyl group cleavage and silicone grease activation S Caddick, FGN Cloke, PB Hitchcock, AKK Lewis, AKDEK LEWIS Angewandte Chemie (International ed.) 43 (43), 5824-5827, 2004 | 192 | 2004 |
Next generation maleimides enable the controlled assembly of antibody–drug conjugates via native disulfide bond bridging FF Schumacher, JPM Nunes, A Maruani, V Chudasama, MEB Smith, ... Organic & biomolecular chemistry 12 (37), 7261-7269, 2014 | 180 | 2014 |
In situ maleimide bridging of disulfides and a new approach to protein PEGylation FF Schumacher, M Nobles, CP Ryan, MEB Smith, A Tinker, S Caddick, ... Bioconjugate chemistry 22 (2), 132-136, 2011 | 180 | 2011 |
Polymeric dibromomaleimides as extremely efficient disulfide bridging bioconjugation and pegylation agents MW Jones, RA Strickland, FF Schumacher, S Caddick, JR Baker, ... Journal of the American Chemical Society 134 (3), 1847-1852, 2012 | 177 | 2012 |
Suzuki–Miyaura cross-coupling of aryl and alkyl halides using palladium/imidazolium salt protocols K Arentsen, S Caddick, FGN Cloke, AP Herring, PB Hitchcock Tetrahedron letters 45 (17), 3511-3515, 2004 | 165 | 2004 |
Synthetic, structural, and mechanistic studies on the oxidative addition of aromatic chlorides to a palladium (N-heterocyclic carbene) complex: relevance to catalytic amination AKK Lewis, S Caddick, FGN Cloke, NC Billingham, PB Hitchcock, ... Journal of the American Chemical Society 125 (33), 10066-10073, 2003 | 161 | 2003 |
Tuning the reactivity of dirhodium (II) complexes with axial N-heterocyclic carbene ligands: the arylation of aldehydes PMP Gois, AF Trindade, LF Veiros, V Andre, MT Duarte, CAM Afonso, ... University of Sussex, 2007 | 139 | 2007 |
Functional native disulfide bridging enables delivery of a potent, stable and targeted antibody–drug conjugate (ADC) JPM Nunes, M Morais, V Vassileva, E Robinson, VS Rajkumar, ... Chemical communications 51 (53), 10624-10627, 2015 | 135 | 2015 |
Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis CP Ryan, MEB Smith, FF Schumacher, D Grohmann, D Papaioannou, ... Chemical communications 47 (19), 5452-5454, 2011 | 126 | 2011 |
Inhibition of HIV‐1 Replication by Isoxazolidine and Isoxazole Sulfonamides B Loh, L Vozzolo, BJ Mok, CC Lee, RJ Fitzmaurice, S Caddick, A Fassati Chemical Biology & Drug Design 75 (5), 461-474, 2010 | 125 | 2010 |
Bromopyridazinedione-mediated protein and peptide bioconjugation V Chudasama, MEB Smith, FF Schumacher, D Papaioannou, G Waksman, ... Chemical communications 47 (31), 8781-8783, 2011 | 121 | 2011 |