A temporal switch in the germinal center determines differential output of memory B and plasma cells FJ Weisel, GV Zuccarino-Catania, M Chikina, MJ Shlomchik Immunity 44 (1), 116-130, 2016 | 535 | 2016 |
Interferon-γ drives Treg fragility to promote anti-tumor immunity AE Overacre-Delgoffe, M Chikina, RE Dadey, H Yano, EA Brunazzi, ... Cell 169 (6), 1130-1141. e11, 2017 | 530 | 2017 |
Adaptive plasticity of IL-10+ and IL-35+ Treg cells cooperatively promotes tumor T cell exhaustion DV Sawant, H Yano, M Chikina, Q Zhang, M Liao, C Liu, DJ Callahan, ... Nature immunology 20 (6), 724-735, 2019 | 374 | 2019 |
Individual variation in susceptibility or exposure to SARS-CoV-2 lowers the herd immunity threshold MGM Gomes, MU Ferreira, RM Corder, JG King, C Souto-Maior, ... Journal of theoretical biology 540, 111063, 2022 | 301 | 2022 |
Treg cells promote the SREBP1-dependent metabolic fitness of tumor-promoting macrophages via repression of CD8+ T cell-derived interferon-γ C Liu, M Chikina, R Deshpande, AV Menk, T Wang, T Tabib, EA Brunazzi, ... Immunity 51 (2), 381-397. e6, 2019 | 222 | 2019 |
Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis FJ Weisel, SJ Mullett, RA Elsner, AV Menk, N Trivedi, W Luo, ... Nature immunology 21 (3), 331-342, 2020 | 198 | 2020 |
Hundreds of genes experienced convergent shifts in selective pressure in marine mammals M Chikina, JD Robinson, NL Clark Molecular biology and evolution 33 (9), 2182-2192, 2016 | 151 | 2016 |
LAG3 limits regulatory T cell proliferation and function in autoimmune diabetes Q Zhang, M Chikina, AL Szymczak-Workman, W Horne, JK Kolls, ... Science immunology 2 (9), eaah4569, 2017 | 138 | 2017 |
Subterranean mammals show convergent regression in ocular genes and enhancers, along with adaptation to tunneling R Partha, BK Chauhan, Z Ferreira, JD Robinson, K Lathrop, KK Nischal, ... Elife 6, e25884, 2017 | 131 | 2017 |
Assessing significance in a Markov chain without mixing M Chikina, A Frieze, W Pegden Proceedings of the National Academy of Sciences 114 (11), 2860-2864, 2017 | 121 | 2017 |
Modeling a human hepatocellular carcinoma subset in mice through coexpression of met and point‐mutant β‐catenin J Tao, E Xu, Y Zhao, S Singh, X Li, G Couchy, X Chen, J Zucman‐Rossi, ... Hepatology 64 (5), 1587-1605, 2016 | 121 | 2016 |
Kidney-infiltrating T cells in murine lupus nephritis are metabolically and functionally exhausted JS Tilstra, L Avery, AV Menk, RA Gordon, S Smita, LP Kane, M Chikina, ... The Journal of clinical investigation 128 (11), 4884-4897, 2018 | 118 | 2018 |
Global Prediction of Tissue-Specific Gene Expression and Context-Dependent Gene Networks in Caenorhabditis elegans MD Chikina, C Huttenhower, CT Murphy, OG Troyanskaya PLoS computational biology 5 (6), e1000417, 2009 | 115 | 2009 |
CellCODE: a robust latent variable approach to differential expression analysis for heterogeneous cell populations M Chikina, E Zaslavsky, SC Sealfon Bioinformatics 31 (10), 1584-1591, 2015 | 110 | 2015 |
Pathway-level information extractor (PLIER) for gene expression data W Mao, E Zaslavsky, BM Hartmann, SC Sealfon, M Chikina Nature methods 16 (7), 607-610, 2019 | 90 | 2019 |
Wnt signaling regulates hepatobiliary repair following cholestatic liver injury in mice H Okabe, J Yang, K Sylakowski, M Yovchev, Y Miyagawa, S Nagarajan, ... Hepatology 64 (5), 1652-1666, 2016 | 86 | 2016 |
The Sleipnir library for computational functional genomics C Huttenhower, M Schroeder, MD Chikina, OG Troyanskaya Bioinformatics 24 (13), 1559-1561, 2008 | 85 | 2008 |
RERconverge: an R package for associating evolutionary rates with convergent traits A Kowalczyk, WK Meyer, R Partha, W Mao, NL Clark, M Chikina Bioinformatics 35 (22), 4815-4817, 2019 | 80 | 2019 |
Ancient convergent losses of Paraoxonase 1 yield potential risks for modern marine mammals WK Meyer, J Jamison, R Richter, SE Woods, R Partha, A Kowalczyk, ... Science 361 (6402), 591-594, 2018 | 75 | 2018 |
A benchmark for evaluation of algorithms for identification of cellular correlates of clinical outcomes N Aghaeepour, P Chattopadhyay, M Chikina, T Dhaene, S Van Gassen, ... Cytometry Part A 89 (1), 16-21, 2016 | 64 | 2016 |