Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale X Li, Z Li, H Zhou, SM Gaynor, Y Liu, H Chen, R Sun, R Dey, DK Arnett, ... Nature genetics 52 (9), 969-983, 2020 | 208 | 2020 |
Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection SM Zekavat, SH Lin, AG Bick, A Liu, K Paruchuri, C Wang, MM Uddin, ... Nature medicine 27 (6), 1012-1024, 2021 | 145 | 2021 |
Deep learning of the retina enables phenome-and genome-wide analyses of the microvasculature SM Zekavat, VK Raghu, M Trinder, Y Ye, S Koyama, MC Honigberg, Z Yu, ... Circulation 145 (2), 134-150, 2022 | 120 | 2022 |
Proteomic profiling platforms head to head: leveraging genetics and clinical traits to compare aptamer-and antibody-based methods DH Katz, JM Robbins, S Deng, UA Tahir, AG Bick, A Pampana, Z Yu, ... Science Advances 8 (33), eabm5164, 2022 | 113 | 2022 |
Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease MM Uddin, NQH Nguyen, B Yu, JA Brody, A Pampana, T Nakao, ... Nature communications 13 (1), 5350, 2022 | 55 | 2022 |
Whole genome sequence analysis of the plasma proteome in black adults provides novel insights into cardiovascular disease DH Katz, UA Tahir, AG Bick, A Pampana, D Ngo, MD Benson, Z Yu, ... Circulation 145 (5), 357-370, 2022 | 55 | 2022 |
Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential T Nakao, AG Bick, MA Taub, SM Zekavat, MM Uddin, A Niroula, CL Carty, ... Science advances 8 (14), eabl6579, 2022 | 51 | 2022 |
Whole genome sequence analysis of blood lipid levels in> 66,000 individuals MS Selvaraj, X Li, Z Li, A Pampana, DY Zhang, J Park, S Aslibekyan, ... Nature communications 13 (1), 5995, 2022 | 47 | 2022 |
Whole genome association study of the plasma metabolome identifies metabolites linked to cardiometabolic disease in black individuals UA Tahir, DH Katz, J Avila-Pachecho, AG Bick, A Pampana, JM Robbins, ... Nature communications 13 (1), 4923, 2022 | 36 | 2022 |
Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins SA Khetarpal, C Vitali, MG Levin, D Klarin, J Park, A Pampana, JS Millar, ... PLoS genetics 17 (9), e1009802, 2021 | 36 | 2021 |
Fibrillar collagen variants in spontaneous coronary artery dissection SM Zekavat, EL Chou, M Zekavat, A Pampana, K Paruchuri, ... JAMA cardiology 7 (4), 396-406, 2022 | 29 | 2022 |
Apolipoprotein B is an insufficient explanation for the risk of coronary disease associated with lipoprotein (a) M Trinder, SM Zekavat, MM Uddin, A Pampana, P Natarajan Cardiovascular Research 117 (5), 1245-1247, 2021 | 22 | 2021 |
Proteomic profiling in biracial cohorts implicates DC-SIGN as a mediator of genetic risk in COVID-19 DH Katz, UA Tahir, D Ngo, M Benson, AG Bick, A Pampana, Y Gao, ... MedRxiv, 2020.06. 09.20125690, 2020 | 22 | 2020 |
Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices P Natarajan, A Pampana, SE Graham, SE Ruotsalainen, JA Perry, ... Nature communications 12 (1), 2182, 2021 | 19 | 2021 |
Association of a multiancestry genome-wide blood pressure polygenic risk score with adverse cardiovascular events V Parcha, A Pampana, NS Shetty, MR Irvin, P Natarajan, HJ Lin, X Guo, ... Circulation: Genomic and Precision Medicine 15 (6), e003946, 2022 | 16 | 2022 |
Lipoprotein (a) and coronary artery disease risk without a family history of heart disease P Finneran, A Pampana, SA Khetarpal, M Trinder, AP Patel, K Paruchuri, ... Journal of the American Heart Association 10 (5), e017470, 2021 | 16 | 2021 |
Cold shock domaincontaining protein E1 is a posttranscriptional regulator of the LDL receptor JSC Geoffrey A. Smith, Arun Padmanabhan, Bryan H. Lau, Akhil Pampana, Li Li ... SCIENCE TRANSLATIONAL MEDICINE 14 (662), 2022 | 10 | 2022 |
Bidirectional Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of intermediate potential T Nakao, AG Bick, MA Taub, SM Zekavat, MM Uddin, A Niroula, CL Carty, ... medRxiv, 2021.02. 26.21252199, 2021 | 8 | 2021 |
Sex differences in the association of genome-wide systolic blood pressure polygenic risk score with hypertension NS Shetty, A Pampana, N Patel, P Li, K Yerabolu, M Gaonkar, G Arora, ... Circulation: Genomic and Precision Medicine 16 (6), e004259, 2023 | 3 | 2023 |
CSDE1 is a post-transcriptional regulator of the LDL receptor GA Smith, A Padmanabhan, BH Lau, A Pampana, L Li, Y Clara Lee, ... bioRxiv, 2020.08. 03.235028, 2020 | 3 | 2020 |